Macrogen provides personalized single cell multi-omics analysis services based on extensive experience and innovation.
Single-cell gene sequencing is used to analyze gene expression profile and genetic changes in a single cell, which is a functional and structural unit of an organism. As it becomes possible to determine cellular heterogeneity, rare cell population, cellular differentiation, chromatin heterogeneity, immune profile, and surface protein profile in a single cell unit, this technique is applied to various fields of research including selection of cell treatments, stem cells, and cancer development and progression. Macrogen quickly provides a high level of genetic sequencing data based on its ability to perform NGS (next generation sequencing), which ranks first in Korea and fifth in the world. Furthermore, we are leading the market by diversifying single-cell sequencing services, thanks to industry-leading genome sequencing expertise accumulated over 26 years and investment in big data and unexplored areas.
Macrogen provides spatial multi-omics services utilizing cutting-edge platforms from global leading companies such as 10x Genomics and Bruker (including Visium, Xenium, CosMX, and GeoMX). Backed by South Korea's top-ranked and the world's 5th-ranked Next Generation Sequencing (NGS) capabilities, alongside the latest in situ-based spatial analysis technologies, Macrogen delivers high-quality data optimized for research objectives in a rapid timeframe. By pioneering technology adoption and service expansion, Macrogen stands as the optimal partner for researchers in the field of spatial multi-omics analysis.
PLATFORM
NGS-based Spatial omics
In situ-based Spatial omics
Visium Spatial
Uncover the whole transcriptome with spatial context


Visium : Sample Preparation
|
FF (Fresh Frozen) |
FFPE (Formalin Fixed Paraffin Embedded) |
Sectioned slide | |
|---|---|---|---|
| Sample type | OCT (compound) block | Paraffin block | FF / FFPE |
| Section Thickness | 10 μm | 5 μm | FF 10µm / FFPE 5µm |
| RNA Quality | RIN ≥ 7 | DV200 ≥ 50% | FF RIN ≥ 4 / FFPE DV200 ≥ 30% |
| Species | Any organism (poly A tail) | Only Human, Mouse | Only Human, Mouse |
*ROI : Region of interest
GeoMx® DSP
Discover Where Biology Happens


| Platform | GeoMx® Digital Spatial Profiler |
|---|---|
| Sample |
FFPE Block (Storage period: 3 years / 35.3mm x 14.1 mm x 4-6 µm / Core Needle Biopsy available) Fresh Frozen Tissue (Store at -80℃, in cutting, within 6 months/ 35.3mm x 14.1 mm x 4-6 µm ) |
| Panel | Human Whole Transcriptome Atlas (hWTA) |
Xenium In Situ
High-plex in situ from the single cell leader


| Platform | Xenium In Situ Analyzer |
|---|---|
| TAT | 6 Weeks |
| Sample type | FFPE, Fresh Frozen Tissue |
| RNA & Protein Assay |
Human Breast Gene Expression Panel (280 genes + Customize up to 100 genes) Extensive panel roadmap (Human Brain, Lung, Skin, Kidney, Pancreas) Various RNA targets analysis can be provided upon request |
| Prime 5K | Human pan tissue and pathways (5001 genes) |
Add on up to 100 genes |
|---|---|---|
| Mouse pan tissue and pathways (5006 genes) | ||
| Xenium v1 | Human immuno-oncology (380 genes) | |
| Human breast (280 genes) | ||
| Human lung (289 genes) | ||
| Human brain (266 genes) | ||
| Human multi-tissue & cancer (377 genes) | ||
| Human colon (322 genes) | ||
| Human skin (260 genes) | ||
| Mouse brain (248 genes) | ||
| Mouse multi-tissue (379 genes) |
CosMx™ SMI
The First Fully-Integrated Single-Cell Spatial Biology Solution with the highest plex, multiomic capability and high resolution


| Platform | CosMx™ Spatial Molecular Imager |
|---|---|
| TAT | 5 Weeks after ROI section |
| Sample type |
FFPE Block (Storage period: 3 years / 35.3mm x 14.1 mm x 4-6 µm / Core Needle Biopsy available) Fresh Frozen Tissue (Store at -80℃, in cutting, within 6 months / 35.3mm x 14.1 mm x 4-6 µm ) tissue microarray, organoid sample |
| RNA & Protein Assay |
CosMx™ Human Universal Cell Characterization Panel (RNA, 1000 Plex) CosMx™ Human Immuno-oncology Panel (RNA, 100 Plex) CosMx™ Human Immuno-oncology Panel (Protein, 64 Plex) Please contact us for inquiries about other panel assays We offer simultaneous analysis for RNA and protein from sectioned tissue. |