Proteomics Olink

Discover high-sensitivity, multiplex protein analysis with Olink— optimized for biomarker discovery and multi-omics integration.

Olink leverages Proximity Extension Assay (PEA) technology to deliver high-specificity, high-sensitivity protein quantification. With the ability to measure hundreds of proteins from a single sample, it’s a powerful platform for biomarker discovery, disease profiling, and precision medicine research.

Olink-based (Proteomics)

Proteins are direct indicators of biological activity and disease states, yet have traditionally been harder to access than genomic data. Macrogen bridges this gap by combining Olink protein data with genomic insights, enabling multi-omics analysis for more personalized and predictive research outcomes.

SERVICE

Olink

Using Olink panels, Macrogen supports a full workflow from large-scale screening to target identification and validation — helping researchers accelerate protein biomarker discovery with greater accuracy and scalability.

Olink PEA(Proximity Extension Assay)

Olink’s PEA technology combines immunoassay precision with DNA-based readout. When two DNA-tagged antibodies bind to a target protein, a unique DNA sequence is generated and quantified via qPCR or NGS. This allows for precise, multiplexed measurement of protein biomarkers — even at low concentrations.

Platform Available
Species		 No. of
protein
markers		 No. of
sample
required		 Key features Readout
Technology
Olink® Explore HT Human ~ 5,400 172 / panel
  • Multiplex analysis of 92 protein biomarkers with a wider dynamic range compared to conventional immunoassays.
    		•  NGS
    Olink® Reveal Human ~ 1,000 86 / panel
  • Streamlined proteomics with ~1,000 proteins, easy workflow, and cost-effective implementation for pilot and directional studies.
    		•  NGS
    Olink® Target 48 Human
    Mouse    		 43~45 / panel 40 / panel
  • Multiplex analysis of 43~45 protein biomarkers with a wider dynamic range compared to conventional immunoassays.
  • Available with absolute and relative quantification, with results reported in pg/mL or NPX units
  • 1 human panel and 1 mouse panel available
    • Human Cytokine
    • Mouse Cytokine
    		 qPCR
    Olink® Target 96 Human
    Mouse    		 92 / panel 88 / panel
  • Ultra-high coverage (5,400+ proteins) and high-throughput proteomics for deep discovery and large-scale studies.
  • Relative quantification with results reported in NPX units
  • 14 human panels and 1 mouse panel available
    • Cardiometabolic
    • Cardiovascular Ⅱ
    • Cardiovascular Ⅲ
    • Cell Regulation
    • Development
    • Immune Response
    • Immuno-Oncology
    • Inflammation
    • Metabolism
    • Neurology
    • Neuro Exploratory
    • Organ Damage
    • OncologyⅡ
    • Oncology Ⅲ
    • Mouse Exploratory
    		 qPCR
    [Contact us for consultation]
    • Customization options are available for Olink® Focus & Olink® Flex.
    • 40 µL of serum or plasma is required. Other sample types (e.g., tissue, cells, CCM, CSF etc.) are also supported.
    • If your sample quantity is below the recommended amount, please contact us for consultation.
    Analysis
    Areas of Analysis Description
    Data analysis of DE Basic statistics(Fold change, group mean, sd etc.)
    Identifying differentially expressed protein(T-test, Mann-Whitney U test, etc.)
    Multiple testing correction (FDR, Bonferroni etc.)
    Clustering Analysis for DEP ( Hierarchical clustering, etc.)
    Functional analysis Pathway Enrichment (Gene Set Enrichment Analysis (GSEA) /
    Over-representation Analysis (ORA))

    Olink Publication

    You can find a list of recent publications using Olink by visiting the link below.
    Olink Publication : https://olink.com/resources-support/publications-2/

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